By State · SAMHSA-verified directory
Addiction treatment in Missouri
338 verified treatment centers across Missouri. Overdose rate 35.0 per 100,000 (CDC 2023) · Medicaid expanded.
338
Centers
20
Cities
Expanded
Medicaid
24/7
Helpline
Treatment centers in Missouri
Every listing sourced from SAMHSA Treatment Services Locator.
Compass Health Mukilteo Evaluation and Treatment
Sullivan, MO
Compass Health Network
Sullivan, MO
Child and Family Guidance Center Antelope Valley Services
Saint Joseph, MO
ReDiscover
Lees Summit, MO
Saint Louis Veterans Affairs Med
Saint Louis, MO
Compass Whole Health
Salisbury, MO
Child and Family Guidance Center Greenville Clinic
Saint Joseph, MO
Comprehensive Health System
New London, MO
ProHealth Care Medical Group Clinic Oconomowoc
Joplin, MO
Child and Family Guidance Center South Dallas
Saint Joseph, MO
Compass Health Raymore
Sullivan, MO
Clementine St. Louis
Saint Louis, MO
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Cities in Missouri with verified facilities
20 cities. Click through for city-specific listings.
Sullivan
49 centers
Kansas City
45 centers
Saint Joseph
35 centers
Saint Louis
32 centers
Joplin
25 centers
Salisbury
23 centers
Milan
19 centers
Springfield
9 centers
Moberly
6 centers
Independence
5 centers
Farmington
5 centers
Carthage
5 centers
Scott City
4 centers
O Fallon
4 centers
Lamar
3 centers
Fulton
3 centers
West Plains
2 centers
Poplar Bluff
2 centers
New London
2 centers
Nevada
2 centers
Understanding treatment in Missouri
There is no gentle way to start this. Missouri has 338 licensed addiction-treatment facilities, a specific place in the Midwest, and a specific version of the national crisis. The specific version matters, because a conversation that works for a family in another state will not land the same way here.
The Medicaid question
Before you look at specific programs, look at Medicaid: Missouri expanded Medicaid in 2021 under the Affordable Care Act. Has realistic access to Medicaid coverage for addiction treatment once enrolled — and that access shapes which facilities can afford to admit non-commercial patients, which in turn shapes the real, reachable network.
The overdose-mortality context
Missouri's overdose rate sits at 35.0 deaths per 100,000 residents annually (CDC, 2023). The national figure is around 31 per 100,000 for comparison. The numbers are uneven within the state — delayed Medicaid expansion leaves transitional gaps in provider-network adequacy — but the trend since the arrival of fentanyl in the local drug supply has shifted the shape of the crisis in ways that older treatment frameworks were not built for.
How access actually works in Missouri
Treatment access in Missouri varies more than most national overviews acknowledge. delayed Medicaid expansion leaves transitional gaps in provider-network adequacy — which does not mean treatment is unavailable, but does mean the usual advice ("call five centers, compare benefits, tour facilities") takes longer here than it would elsewhere. The practical version: start with your insurance's behavioral-health line, ask for a list of in-network facilities within 25 miles, then cross-reference with the SAMHSA federal locator to see what is actually operating.
What to do next
Practically, the next step for someone in Missouri considering treatment is usually one of these three: take the Self-Assessment on this site to understand severity (this does not commit you to anything and your answers stay in your browser); call the SAMHSA National Helpline at 1-800-662-HELP for a neutral federal assessment of options; or call the insurance plan's behavioral-health line to request a list of in-network facilities offering MAT. Any of the three are reasonable first moves; none require a decision today.
Last updated April 2026. Sources: SAMHSA Treatment Locator, CDC WONDER (overdose mortality 2023), KFF Medicaid Tracker, ASAM Criteria 4e. See our editorial policy.